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當(dāng)前位置:首頁產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2141CD63 Recombinant Rabbit mAb (SDT-230-3)

CD63 Recombinant Rabbit mAb (SDT-230-3)
產(chǎn)品簡介:

CD63 Recombinant Rabbit mAb (SDT-230-3)

產(chǎn)品型號:S0B2141

更新時間:2025-10-09

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CD63 is a member of the tetraspanin superfamily, a cluster of cell surface associated membrane proteins with four transmembrane domains [PubMed: 31882993, PubMed: 25921073]. Tetraspanins have been shown to be involved in many cellular functions including cell motility, adhesion, differentiation,activation, immune response, and tumor cell migration and invasion. Post translational modification of CD63 results in its ability to organize and form tetraspanin-enriched microdomains (TEMs) on membranes. The formation of TEMs allows interaction with components such as integrin molecules, immunoglobulins, proteoglycans, cadherins, and signaling molecules on the cell surface [PubMed: 31882993, PubMed: 15992681]. CD63 is highly enriched in late endosomal and lysosomal compartments after being endocytosed from the cell surface through the clathrin-coated vesicles.

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