13774214275
13774214275
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產品型號：S0B2375
更新時間：2025-10-11
廠商性質：生產廠家
訪問量：273
服務熱線15855403091
相關文章
ALPP/ALPPL2 proteins are members of the alkaline phosphatase family, which are closely related and regulated GPI-anchored proteins. ALPP, also known as placental alkaline phosphatase, and ALPPL2, also known as germ cell alkaline phosphatase or placental-like alkaline phosphatase 2, share a high degree of amino acid sequence similarity （98% homology） and have a highly restricted tissue expression pattern, primarily found in placental trophoblasts and certain tumor tissues. ALPPL2 is expressed in various cancers, including mesothelioma, ovarian cancer, and gastric cancer, and is considered a tumor-specific antigen due to its high tissue specificity. This makes it a promising target for cancer therapies, such as antibody-drug conjugates and CAR-T cell therapies.
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