13774214275
13774214275
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產品型號：S0B2378
更新時間：2025-10-11
廠商性質：生產廠家
訪問量：278
服務熱線15855403091
相關文章
Brachyury protein is a transcription factor encoded by the TBXT gene, belonging to the T-box family of genes. It plays a crucial role in embryonic development, particularly in the formation and differentiation of the mesoderm and the notochord, which is the precursor of the spinal column. In adults, Brachyury is almost exclusively expressed in notochord-derived cells. Abnormal expression of Brachyury has been associated with certain cancers, such as chordoma, a malignant tumor that arises from residual notochordal cells. Additionally, it is involved in the epithelial-mesenchymal transition （EMT） in various carcinomas, promoting tumor invasion and metastasis.
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