13774214275
13774214275
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產品型號：S0B2373
更新時間：2025-10-11
廠商性質：生產廠家
訪問量：249
服務熱線15855403091
相關文章
NPHS1 protein, also known as nephrin, is a type-1 transmembrane protein primarily found in renal tissues, specifically at the slit diaphragm of glomerular podocytes. It is a member of the immunoglobulin family of cell adhesion molecules and plays a crucial role in the glomerular filtration barrier, functioning as an ultrafilter to exclude albumin and other plasma macromolecules from urine. Mutations in the NPHS1 gene can lead to Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
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