13774214275
13774214275
產品中心
產品型號：S0C3050
更新時間：2025-10-11
廠商性質：生產廠家
訪問量：259
服務熱線15855403091
相關文章
Interleukin 10 （IL-10）, also known as human cytokine synthesis inhibitory factor （CSIF）, is an anti-inflammatory cytokine. In humans, IL-10 is primarily produced by monocytes and, to a lesser extent, lymphocytes, namely type-II T helper cells （TH2）, mast cells, CD4+CD25+Foxp3+ regulatory T cells, and in a certain subset of activated T cells and B cells. IL-10 can be produced by monocytes upon PD-1 triggering in these cells. IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway.
當前位置：
上一個：
返回列表
